News Reports & Publications

B. subtilis LytR-CpsA-Psr Enzymes Transfer Wall Teichoic Acids from Authentic Lipid-Linked Substrates to Mature Peptidoglycan In Vitro

 

October 10th, 2016 – The assemblage of glycopolymers within the peptidoglycan cell wall of Gram-positive bacteria is crucial for viability and pathogenesis. However, the molecular process by which this function is executed is poorly understood. In Dr. Eric Brown’s most recent publication in Cell Chemical Biology, Ph.D. candidate Robert Gale and colleagues shed light on the molecular features of glycopolymer transfer, with the aim of aiding drug discovery and development programs which exploit this antibacterial target.

Read the full publication in Cell Chemical Biology.

Visit www.brownlab.ca to learn more about the research happening in Dr. Eric Brown‘s lab.