Institute of Infectious Disease Research member Dr. Tohid Didar.
Hamilton, Ontario, September 14th, 2017 – McMaster University scholars have developed a novel technique to minimize the ongoing problem of catheter-associated blood clotting.
In collaboration with the Thrombosis & Atherosclerosis Research Institute (TaARI) and McMaster Department of Mechanical Engineering, researchers within IIDR member Dr. Tohid Didar’s lab at the McMaster University School of Biomedical Engineering developed a substance that can be applied to catheters to lower the risk of blood thrombosis.
Didar’s omniphobic, lubricant-infused catheter coating produced through chemical vapor disposition (CVD) of hydrophobic organosilanes significantly reduces blood clotting when compared with uncoated catheters. Further, the CVD catheters are more efficient in preventing blood coagulation than other commonly used coating techniques, as well as more reproducible and less disruptive to the catheters.
The CVD method is a simple, straightforward, and non-invasive procedure, with the potential to not only prevent catheter thrombosis, but also thrombosis associated with other widely used blood contacting medical devices, such as heart valves and vascular grafts. Such innovations further lead to less delay in treatment, reduced hospital stay, and lower heath care costs for patients.
Read the full publication at www.nature.com/articles/s41598-017-12149-1.
Correspondence and requests for materials should be addressed to T.F.D. (email: [email protected]).