Jakob Magolan, PhD
Associate Professor, Department of Biochemistry and Biomedical Sciences
905-525-9140 ext. 22268
McMaster University, MDCL 2306
1200 Main Street West
Hamilton, ON
L8N 3Z5
The Magolan laboratory engages in hit-to-lead synthetic medicinal chemistry. We synthesize small focused libraries of compounds based on hits identified via high-throughput antimicrobial screening campaigns. In collaboration with biologists, we employ iterative hypothesis-driven approaches to optimize efficacy and desirable pharmacokinetic properties of lead compounds in order to enable their advancement to further stages of the drug development process.