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Dr. Jianping Xu’s lab finds limited evidence of fungicide-driven triazole resistant Aspergillus fumigatus in Hamilton, Canada

 

Dr. Jianping Xu, Professor, Department of Biology

Over the past several years, there have been growing health concerns suggesting fungicides as a major contributor to the rise of triazole resistant and life-threatening Aspergillus fumigatus fungi (read here). In response to this concern, Dr. Jianping Xu’s lab showed evidence of decreased triazole susceptibility in both clinical and agriculturalisolates when compared to urban isolates, suggesting that agricultural triazole fungicide use has not caused triazole resistance among clinical samples of A. fumigatus in Hamilton. They note, however, that continued triazole selection pressure could drive some of the Hamiltonian isolates to become resistant, and that other Canadian regions could have such a link.

 

Read the full publication in the Canadian Journal of Microbiology.